Treatment involves chemotherapy, followed by a stem cell transplant.
Stem cells have a natural ‘homing’ ability, which can be used to transport an anti-cancer gene called MSCTRAIL to the site of malignant tumours. In England, scientists at University College London are using mesenchymal stem cells to treat lung cancer. Researchers hope that the anti-inflammatory properties of stem cells will reverse lung damage. Recently, doctors at Monash Children’s Hospital, Victoria saw success using placenta stem cells to treat a lung condition called bronchopulmonary dysplasia, which affects premature babies after they have been supported by respiratory apparatus. Of these, there are 51 looking at lung cancer, 15 at COPD, and 22 at pneumonia. There are 197 clinical trials testing stem cell therapies for the treatment of lung disease.
Only 40% of people treated for lung cancer respond to therapy. Lung cancer rates have risen 23% since 2004 Although various treatment options for COPD exist, none has been found to repair or reverse emphysematous destruction of the lung. In this paper, we review the current evidence of stem cell therapy in COPD. Previous studies suggest that cell-based therapies and novel bioengineering approaches may be potential therapeutic strategies for lung repair and remodelling. COPD is the second most common lung disease Currently the research is in its infancy however, the field is profoundly growing. 3 million people living with COPD, 2 million undiagnosed. Adults over 65 are at a much higher risk of contracting lung disease. 6.5 million people currently treated for lung disease in the UK. 10,000 people newly diagnosed with lung disease every week. In the UK, someone dies from lung disease every 5 minutes Preclinical studies suggest that mesenchymal stem cells (MSCs) may provide a therapeutic option for this incurable disease because of their antiinflammatory. Overall, lung disease is responsible for 20.1% of deaths in the UK every year. Pneumonia causes 25.3% of lung-related deaths. Patients’ air sacs fill with pus and sometimes turn solid. Pneumonia is lung inflammation caused by a bacterial or viral infection. COPD accounts for 26.1% of UK lung-related deaths. Chronic obstructive pulmonary disease (COPD) refers to a range of conditions, including bronchitis, emphysema, refractory asthma and more. Lung cancer is responsible for 31% of lung-related deaths in the UK. Usually, this occurs in cells in the air passages, which then turn into tumours. Lung cancer is the growth of abnormal cells in one or both of the lungs. There are more activated macrophages and fibroblasts found in alveoli of COPD lungs and these. Of the many lung conditions affecting patients today, there are three illnesses which are most common: The environment surrounding the stem cell also changes in disease. The causes vary from smoking to diet, to premature birth and old age. Lung disease refers to a range of medical conditions affecting the respiratory organs.
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